SCUBA

FAM53C — Family with sequence similarity 53 member C

FAM53C belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FAM53C's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsImmediate early response
Stress		ABHD5, CEBPB, CITED2, GADD45A, GADD45B, HEXIM1, HSPA2, IER5L +9 moreView in SCUBA
CD4⁺ T cellsPol II Transcription Regulation
DNA/chromatin regulation		ABHD5, BAIAP2, BRD2, CBX4, CDKN1C, CITED2, CKS2, EHD1 +28 moreView in SCUBA
FibroblastsHypoxia-driven EMT
Stress		ARC, CITED2, CSKMT, DDIT4, FAM43A, HBEGF, HEXIM1, IER5L +7 moreView in SCUBA
Gamma-delta T cellsStress Epigenetic Silencing
DNA/chromatin regulation		ALKBH5, ANKHD1, EPC2, MXD1, NEU1, OTUD4, PHF1, PNO1 +8 more
Glial cellsDNA Damage Response
Stress		BRD2, GADD45B, IER5, ING1, NFKBIZ, PABPC1, SRSF3, TUBB4B +1 moreView in SCUBA
Innate lymphoid cellsTranscriptional Activation
DNA regulation & transcription		AKIRIN1, CHORDC1, FAM133B, GOLGB1, GTF2B, IDI1, MORF4L2, NABP1 +9 moreView in SCUBA
MacrophagesSplicing Factor Regulation
Housekeeping		ARAP1, CCNL1, CELF1, CLK1, IFRD1, INPPL1, KIDINS220, MAN2C1 +12 moreView in SCUBA
Mucosal-associated invariant T cellIntegrated Stress Response
Stress		ATF4, EIF4A3, EIF5, IFRD1, MARCKSL1, MKNK2, ODC1, PLK2 +7 more
Natural Killer cellsTranscription Elongation Control
DNA regulation & transcription		C6orf62, FUS, HEXIM1, INTS6, MAT2A, NABP1, PCF11, PPP1R10 +2 moreView in SCUBA
Smooth muscle cellsTranslation initiation/RNA-binding
RNA processing & translation		BRI3, CDV3, EIF5, EPC1, FAM133B, FUS, MAFB, PPP1R10 +2 moreView in SCUBA

About the gene

SynonymsC5orf6
Chromosome5: 138331935-138349729
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.