SLC38A4 — Solute carrier family 38 member 4
SLC38A4 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC38A4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Mature Colonocyte Metabolism Nutrient processing | ACADS, ACSF2, ADIRF, AGFG2, B4GALNT2, CA1, CA2, CHP2 +37 more | View in SCUBA |
About the gene
| Synonyms | ATA3, NAT3, PAAT |
|---|---|
| Chromosome | 12: 46764761-46832408 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Amino-acid transport, Ion transport, Sodium transport, Symport, Transport |
Function
Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+). Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L- proline and L-glutamine and L-methionine.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.