SLC4A3 — Solute carrier family 4 member 3
SLC4A3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC4A3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Myeloid Innate Immune Myeloid development | CCR2, CUX2, CYBB, FXYD7, KCNC3, KIF17, NFKB1, PLD4 +5 more |
About the gene
| Synonyms | AE3, SLC2C |
|---|---|
| Chromosome | 2: 219627394-219641980 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Anion exchange, Antiport, Ion transport, Transport |
Function
Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.