TIFAB — TIFA inhibitor
TIFAB belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TIFAB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Inflammasome Pyroptosis Inflammatory | ARRDC1, ATOX1, CSTA, EMP2, ENPP2, FBXO6, GSDMD, HLA-DQB2 +12 more | View in SCUBA |
About the gene
| Chromosome | 5: 135444226-135452351 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.