SCUBA

TM6SF2 — Transmembrane 6 superfamily member 2

TM6SF2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TM6SF2's module in each cell type

Cell typeModuleShares the module with
ColonocytesInflammatory Colonocyte State
Inflammation
ABCA5, ALDOB, CYBRD1, DNAH7, FMO5, GALNT12, MUC2, NHSL1 +6 moreView in SCUBA

About the gene

SynonymsLpr4
Chromosome19: 19264364-19273391
Predicted locationMembrane
Essential geneNo
Protein classHuman disease related genes, Predicted membrane proteins, Transporters
Biological processLipid metabolism

Function

Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.