TMEFF2 — Transmembrane protein with EGF like and two follistatin like domains 2
TMEFF2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEFF2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Wnt-niche Fibroblast Developmental | ALDH1A1, APCDD1L, CAPN6, CCDC80, EBF1, FGL2, IGF1, MEOX2 +5 more | View in SCUBA |
About the gene
| Synonyms | CT120.2, HPP1, TENB2, TPEF, TR |
|---|---|
| Chromosome | 2: 191949043-192194933 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Predicted secreted proteins |
Function
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.