FGL2 — Fibrinogen like 2
FGL2 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FGL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | YAP Mechanotransduction migration & adhesion | COBLL1, CREB5, DEPP1, DST, FLNC, FN1, GCNT2, GLIPR2 +7 more | View in SCUBA |
| Fibroblasts | Wnt-niche Fibroblast Developmental | ALDH1A1, APCDD1L, CAPN6, CCDC80, EBF1, IGF1, MEOX2, MGP +5 more | View in SCUBA |
| Gamma-delta T cells | Cytotoxic Effector Program cytotoxicity | ADGRG1, ANXA4, CADM1, CX3CR1, FCGR3A, FGFBP2, GNLY, GZMB +14 more | |
| Glial cells | Glial ECM Scaffold ECM remodeling | CADM1, COL9A3, FBLN2, ISLR, ITIH5, LTBP4, MAMDC2, PCSK2 +1 more | View in SCUBA |
| Macrophages | Resident Mac Niche Tissue homeostasis | AGGF1, ALDH1A1, ARL5A, CD163L1, CD209, CHN2, CLEC4F, CLIC2 +22 more | View in SCUBA |
| Monocytes | Macrophage Innate Activation Innate immunity | DMXL2, HSD17B4, KCTD12, MPEG1, PTPRC, SAMHD1, TLR4, VPS35 +1 more | View in SCUBA |
| Smooth muscle cells | Microfibrillar ECM Program ECM remodeling | ALDH1A1, CDC42EP3, FOXP2, MAB21L2, MFAP2, NREP, OLFML3, PNCK +2 more | View in SCUBA |
About the gene
| Synonyms | pT49, T49 |
|---|---|
| Chromosome | 7: 77193369-77199848 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
Function
May play a role in physiologic lymphocyte functions at mucosal sites
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.