SCUBA

TMX3 — Thioredoxin related transmembrane protein 3

TMX3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TMX3's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsActin Cytoskeletal Regulation
Cytoskeletal
ACTR2, AP3B1, AP3M1, AZI2, CAPZA1, CEP250, CPSF3, DIDO1 +25 more

About the gene

SynonymsFLJ20793, KIAA1830, PDIA13, TXNDC10
Chromosome18: 68673688-68715108
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Molecular functionIsomerase

Function

Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.