TNNC2 — Troponin C2, fast skeletal type
TNNC2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TNNC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Colonocyte Water Transport Nutrient processing | ABCB1, ABCG2, ACHE, AMACR, ANPEP, AQP7, AQP8, ARHGAP45 +31 more | View in SCUBA |
About the gene
| Synonyms | CFAP85, FAP85 |
|---|---|
| Chromosome | 20: 45823214-45833745 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
| Molecular function | Muscle protein |
Function
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.