TYW3 — TRNA-yW synthesizing protein 3 homolog
TYW3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TYW3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Ribosome Biogenesis Housekeeping | ABCE1, BCCIP, CLPX, COX20, DDX18, DUS1L, EIF3B, IDH3A +17 more | View in SCUBA |
About the gene
| Synonyms | C1orf171, FLJ40918 |
|---|---|
| Chromosome | 1: 74733152-74766678 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Methyltransferase, Transferase |
| Biological process | tRNA processing |
Function
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.