Proteostasis Housekeeping
Gene co-expression module in Neutrophils
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 1 of 5 |
| Annotation consistency | 8 of 17 genes have a known function matching the annotation |
Why this annotation
Small module with weak coherence and diverse housekeeping genes. These cover deubiquitination/proteostasis (ATXN3, USP8, ECPAS, HSPA13, DNAJC5), endocytosis/trafficking (SH3GL1, AP3S1, ZDHHC2), signaling (PIK3CA, PPP2CA, CDKN1B) and transcription (RTF1, SETD2, CPSF2). It likely represents generic proteostasis/trafficking housekeeping noise.
Genes
Most correlated modules
- IL-1 Activation · correlation 0.51
- Generic Housekeeping · correlation 0.49
- Electron Transport Chain · correlation 0.46
- Sparse Housekeeping · correlation 0.42
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.