ABHD17B — Abhydrolase domain containing 17B, depalmitoylase
ABHD17B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ABHD17B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Chromatin Epigenetic Regulation Housekeeping | ANKH, ARHGAP21, CCNH, CTTNBP2NL, DMXL1, EEIG2, ELF2, FBXO34 +21 more | View in SCUBA |
About the gene
| Synonyms | C9orf77, CGI-67, FAM108B1 |
|---|---|
| Chromosome | 9: 71862452-71911193 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.