CTTNBP2NL — CTTNBP2 N-terminal like
CTTNBP2NL belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CTTNBP2NL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Vesicle Trafficking Signaling Housekeeping | ANK1, ANKRA2, B3GALNT2, C1orf216, C22orf39, CASC3, CCDC71L, CD80 +21 more | View in SCUBA |
| Endothelial | Oxidative Stress Response Stress | AHR, CD151, CD59, DSTN, FLOT2, GNB4, GNG5, HYAL2 +11 more | View in SCUBA |
| Lymphatic endothelial | NRF2 Oxidative Stress Stress | B4GALT1, DDX21, DRAM1, GCH1, HNRNPF, MSN, NFE2L2, PDXDC1 +11 more | View in SCUBA |
| Macrophages | Chromatin Epigenetic Regulation Housekeeping | ABHD17B, ANKH, ARHGAP21, CCNH, DMXL1, EEIG2, ELF2, FBXO34 +21 more | View in SCUBA |
About the gene
| Synonyms | DKFZp547A023 |
|---|---|
| Chromosome | 1: 112396214-112463456 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulates lamellipodial actin dynamics in a CTTN-dependent manner (By similarity). Associates with core striatin-interacting phosphatase and kinase (STRIPAK) complex to form CTTNBP2NL-STRIPAK complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.