ADGRE1 — Adhesion G protein-coupled receptor E1
ADGRE1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADGRE1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Non-classical Monocyte Migration Migration & adhesion | CX3CR1, ITGA4, ITGAL, LILRA1, LTB, SCLT1, SH2D3C, UTRN | View in SCUBA |
About the gene
| Synonyms | EMR1, TM7LN3 |
|---|---|
| Chromosome | 19: 6887566-6940459 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
| Biological process | Adaptive immunity, Immunity |
Function
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.