UTRN — Utrophin

UTRN belongs to a gene co-expression module in 15 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

UTRN's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Chromatin Regulation DNA/chromatin regulation	AKAP9, ANKRD12, BBX, CHD2, CHD7, IRF1, KDM7A, L3MBTL3 +8 more	View in SCUBA
CD4⁺ T cells	Immune regulation Immune regulation	DENND1B, FAM111A, GIT2, GOLGA8A, LPIN1, NLRC3, PPP2R5C, PSD4 +5 more	View in SCUBA
Endothelial	Cytoskeletal Scaffolding Cytoskeletal	ADD1, AGPAT1, ANO6, ARL6IP5, CDC42BPA, CHURC1, DOCK1, ERC1 +6 more	View in SCUBA
Enterocytes	Focal adhesion actin Migration & adhesion	BAZ2B, CARMIL1, COP1, FRYL, KIF13A, LPP, MYO6, PALLD +4 more	View in SCUBA
Fibroblasts	TGF-beta Fibroblast Niche ECM production	APCDD1, BAG2, C12orf75, CD55, CES1, CGREF1, COL11A1, CRYAB +8 more	View in SCUBA
Gamma-delta T cells	T Cell Identity Program T cell maturation	ADA2, ADAM10, ARHGAP12, ATM, LPP, NLRC5, PIKFYVE, PJA2 +5 more
Innate lymphoid cells	Cytoskeletal Remodeling Cytoskeleton & motility	BCLAF1, BPTF, CBL, CDK13, IQGAP2, KDM2A, KDM5A, LTC4S +8 more	View in SCUBA
Lymphatic endothelial	Lymphatic Valve Development Valve formation	GPM6A, LRP5, MEF2C, MPP7, NFIA, NFIB, PGM5, PRKAR1B +5 more	View in SCUBA
Macrophages	ER Stress Response Stress	ARHGEF12, ATXN7, BTBD7, CD2AP, CLIP2, DAPK1, DST, ERN1 +14 more	View in SCUBA
Monocytes	Non-classical Monocyte Migration Migration & adhesion	ADGRE1, CX3CR1, ITGA4, ITGAL, LILRA1, LTB, SCLT1, SH2D3C	View in SCUBA
Mucosal-associated invariant T cell	Calcium Signal Integration TCR Signaling	ANKRD44, ARB2A, CAMK2D, DOCK10, ELMO1, EXOC4, FCHSD2, FNDC3A +20 more
Natural Killer cells	IFN-stimulated NK Inflammation	AKNA, APOL6, ATM, CTSC, ITGAL, MBP, MXD1, PILRB +4 more	View in SCUBA
Neutrophils	JAK-MAPK Signaling Inflammatory	CELF2, ENTPD1, GIT2, JAK2, MAPK1, MBNL1, SLMAP, SPTLC2 +1 more
Pericytes	Caveolae Organization Cytoskeletal	CAV1, CAV2, CAVIN1, PDLIM5, PLEC, PLS3, SYNE2	View in SCUBA
Smooth muscle cells	Cytoskeletal Scaffolding Cytoskeletal	AKAP6, C3orf70, CNST, CTTNBP2, DACT3, IQGAP1, KIF13A, KLHL23 +8 more	View in SCUBA

About the gene

Synonyms	DMDL, DRP, DRP1
Chromosome	6: 144285335-144853034
Predicted location	Intracellular
Essential gene	No
Protein class	Plasma proteins, Predicted intracellular proteins
Molecular function	Actin-binding

Function

May play a role in anchoring the cytoskeleton to the plasma membrane

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.