ADGRE3 — Adhesion G protein-coupled receptor E3
ADGRE3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADGRE3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Monocyte-Macrophage Differentiation Developmental | ADGRE2, BID, CYSLTR2, FAM110A, HES4, MARCKSL1, NRARP, PRELID1 +4 more | View in SCUBA |
About the gene
| Synonyms | EMR3 |
|---|---|
| Chromosome | 19: 14619117-14690027 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes- derived macrophages and activated neutrophils
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.