AGAP3 — ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGAP3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AGAP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | NF-κB AP-1 Signaling Inflammatory | ABL2, ARL8B, ATP1B3, ATP6V1H, B4GALT1, C5AR2, CDKN1A, CERT1 +21 more | View in SCUBA |
About the gene
| Synonyms | CENTG3 |
|---|---|
| Chromosome | 7: 151085831-151144436 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.