C1QTNF4 — C1q and TNF related 4
C1QTNF4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
C1QTNF4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Granulocyte Commitment Granulocyte development | C16orf74, CEACAM4, CEBPA, CLEC11A, CPVL, CSF3R, IGFBP2, IGLL1 +6 more |
About the gene
| Synonyms | CTRP4, ZACRP4 |
|---|---|
| Chromosome | 11: 47589667-47594411 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Cytokine |
Function
May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent. Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 hours post-injection (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.