CLEC11A — C-type lectin domain containing 11A
CLEC11A belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLEC11A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | BMP-ECM Fibroblast ECM remodeling | ACVRL1, GNG11, ITGB5, LAMA2, MRC2, TFPI, VCAN | View in SCUBA |
| Hematopoietic progenitor cells | Granulocyte Commitment Granulocyte development | C16orf74, C1QTNF4, CEACAM4, CEBPA, CPVL, CSF3R, IGFBP2, IGLL1 +6 more |
About the gene
| Synonyms | CLECSF3, LSLCL, P47, SCGF |
|---|---|
| Chromosome | 19: 50723364-50725708 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
| Molecular function | Growth factor |
| Biological process | Osteogenesis |
Function
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.