C3AR1 — Complement C3a receptor 1
C3AR1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
C3AR1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Inflammatory effector Immune regulation | CAST, CLDND1, CMTM3, CREB3L2, EIF4E3, EPB41, FYCO1, IL18R1 +9 more | View in SCUBA |
| Macrophages | Myeloid Innate Signaling Innate immunity | ADCY7, ARHGAP18, BMP2K, C6orf62, CD46, CD84, CLTC, CNEP1R1 +34 more | View in SCUBA |
About the gene
| Synonyms | AZ3B, C3AR |
|---|---|
| Chromosome | 12: 8056844-8066359 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
| Biological process | Chemotaxis |
Function
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.