SCUBA

CD300LB — CD300 molecule like family member b

CD300LB belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CD300LB's module in each cell type

Cell typeModuleShares the module with
MonocytesMonocyte Activation State
Inflammatory
ANKRD28, ANXA1, CACNA2D3, JAML, LDLR, METTL7A, MYADM, NRG1View in SCUBA

About the gene

SynonymsCLM7, TREM5
Chromosome17: 74521174-74531475
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classCD markers, Predicted intracellular proteins, Predicted membrane proteins
Molecular functionReceptor
Biological processImmunity

Function

Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.