CDKAL1 — CDK5 regulatory subunit associated protein 1 like 1
CDKAL1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDKAL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | Cilia Centrosome Program Cytoskeletal | ARB2A, BBS9, BCAS3, CEP112, EPB41L4A, FCHSD2, FTO, MBD5 +7 more | View in SCUBA |
About the gene
| Synonyms | FLJ20342 |
|---|---|
| Chromosome | 6: 20534457-21232404 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Transferase |
| Biological process | tRNA processing |
Function
Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.