CEP192 — Centrosomal protein 192
CEP192 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CEP192's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | DNA Damage Response Stress | APAF1, ARHGAP35, ATP11C, ATR, CDC42SE2, CENATAC, CEP85L, EPB41 +19 more | View in SCUBA |
About the gene
| Synonyms | FLJ10352, KIAA1569, PPP1R62 |
|---|---|
| Chromosome | 18: 12991362-13125052 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
Required for mitotic centrosome maturation and bipolar spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Centrosome- specific activating scaffold for AURKA and PLK1.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.