COL7A1 — Collagen type VII alpha 1 chain
COL7A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
COL7A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | MMP-driven Fibroblast Remodeling ECM remodeling | AKR1B1, ANPEP, COL27A1, CTSL, IL7R, INHBA, MME, MMP1 +4 more | View in SCUBA |
About the gene
| Synonyms | EBD1, EBDCT, EBR1 |
|---|---|
| Chromosome | 3: 48564073-48595329 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Protease inhibitor, Serine protease inhibitor |
| Biological process | Cell adhesion |
Function
Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.