CRACD — Capping protein inhibiting regulator of actin dynamics
CRACD belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRACD's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Colonocyte differentiation signaling Epithelial development | APPL2, BTBD9, BTNL8, CA13, DENND5B, LUZP1, NEDD4, RALGPS1 +2 more | View in SCUBA |
About the gene
| Synonyms | CRAD, KIAA1211 |
|---|---|
| Chromosome | 4: 56049098-56330609 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins |
Function
Involved in epithelial cell integrity by acting on the maintenance of the actin cytoskeleton. Positively regulates the actin polymerization, by inhibiting the interaction of actin-capping proteins with actin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.