SCUBA

RALGPS1 — Ral GEF with PH domain and SH3 binding motif 1

RALGPS1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RALGPS1's module in each cell type

Cell typeModuleShares the module with
EnterocytesColonocyte differentiation signaling
Epithelial development
APPL2, BTBD9, BTNL8, CA13, CRACD, DENND5B, LUZP1, NEDD4 +2 moreView in SCUBA

About the gene

SynonymsKIAA0351, RALGEF2, RALGPS1A
Chromosome9: 126914774-127223166
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionGuanine-nucleotide releasing factor

Function

Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.