DENND5B — DENN domain containing 5B
DENND5B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DENND5B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Colonocyte differentiation signaling Epithelial development | APPL2, BTBD9, BTNL8, CA13, CRACD, LUZP1, NEDD4, RALGPS1 +2 more | View in SCUBA |
About the gene
| Synonyms | MGC24039 |
|---|---|
| Chromosome | 12: 31382226-31591136 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Guanine-nucleotide releasing factor |
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.