CRLF1 — Cytokine receptor like factor 1
CRLF1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRLF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | BMP-SMAD Signaling Neroprotection | A2M, AQP1, ARC, CAPS, GDNF, ID1, ID3, NRXN2 +3 more | View in SCUBA |
About the gene
| Synonyms | CISS, CISS1, CLF, CLF-1 |
|---|---|
| Chromosome | 19: 18572220-18607741 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Receptor |
Function
In complex with CLCF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). May also play a regulatory role in the immune system
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.