DMXL2 — Dmx like 2
DMXL2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DMXL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Sphingolipid Membrane Homeostasis Lipid metabolism | ACER3, AGPAT3, ARHGEF11, ATP2A2, C9orf72, CMIP, DOCK8, FOXN2 +12 more | View in SCUBA |
| Monocytes | Macrophage Innate Activation Innate immunity | FGL2, HSD17B4, KCTD12, MPEG1, PTPRC, SAMHD1, TLR4, VPS35 +1 more | View in SCUBA |
About the gene
| Synonyms | DFNA71, KIAA0856, RC3 |
|---|---|
| Chromosome | 15: 51447711-51622833 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters |
Function
May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles. Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.