CMIP — C-Maf inducing protein

CMIP belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CMIP's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Cytotoxic effector Cytotoxicity	ADAP1, ALOX5AP, AOAH, CD244, CPNE7, CRTAM, DAPK2, DOCK5 +15 more	View in SCUBA
CD8⁺ T cells	TCR Proximal Signaling TCR Signaling	ACTN4, CD3G, GALNT1, IVNS1ABP, LCP2, MSN, PTPN22, PTPRA +3 more	View in SCUBA
Endothelial	IL-13/STAT6 Signaling Inflammation	ABLIM1, ARL2BP, ASRGL1, ATP8B1, BMP1, BMPR2, CLIP1, EHBP1L1 +18 more	View in SCUBA
Fibroblasts	Inflammatory TF Response Inflammatory	ADAMTS4, CEBPD, FOSL2, KLF9, MAT2A, NR4A1, NR4A2, NR4A3 +2 more	View in SCUBA
Gamma-delta T cells	TCR Threshold Regulation TCR Signaling	AGO2, ATP8A1, AUTS2, CNOT6L, CSNK1D, FOXO1, GSPT1, MAP3K8 +8 more
Macrophages	Sphingolipid Membrane Homeostasis Lipid metabolism	ACER3, AGPAT3, ARHGEF11, ATP2A2, C9orf72, DMXL2, DOCK8, FOXN2 +12 more	View in SCUBA
Mucosal-associated invariant T cell	Transcriptional Repression Immune regulation	ANKRD11, MXI1, NR3C1, PELI2, PROSER1, RB1CC1, RCOR1, RFTN1 +7 more
Smooth muscle cells	Wnt-Hedgehog Niche Development	ADGRL3, APOC1, CLMP, EDNRB, HSD17B6, IRS1, LTBP3, NPNT +8 more	View in SCUBA

About the gene

Chromosome	16: 81444808-81711762
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins

Function

Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.