ERG — ETS transcription factor ERG
ERG belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ERG's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | HSC Stem Identity Stemness | ANGPT1, APLP2, CALN1, LYSMD2, MSRB3, NPR3, SERPINB6, TFEC | |
| Neutrophils | Myeloid Lipid Remodeling Developmental | ADK, AGPS, ATP8A1, ATP8B4, CLTCL1, DOP1B, GPD2, HNRNPLL +3 more |
About the gene
| Synonyms | erg-3, p55 |
|---|---|
| Chromosome | 21: 38380027-38661780 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.