MSRB3 — Methionine sulfoxide reductase B3
MSRB3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MSRB3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Hippo-YAP Cytoskeletal Cytoskeletal | CSRP1, EHD2, FDPS, FLNA, FLNB, MANSC1, MAP1B, MTCH1 +4 more | View in SCUBA |
| Fibroblasts | Myofibroblast Contractile Cytoskeletal | ACTA2, CCDC107, CFL2, CSRP1, FLNA, ILK, LPP, MYL9 +7 more | View in SCUBA |
| Hematopoietic progenitor cells | HSC Stem Identity Stemness | ANGPT1, APLP2, CALN1, ERG, LYSMD2, NPR3, SERPINB6, TFEC | |
| Neutrophils | Myeloid Maturation Developmental | AFF2, CERS6, DGKG, FAF1, LRMDA, PKP4, RSRC1 |
About the gene
| Synonyms | DFNB74, DKFZp686C1178, FLJ36866 |
|---|---|
| Chromosome | 12: 65278643-65491430 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.