SCUBA

FANCC — FA complementation group C

FANCC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FANCC's module in each cell type

Cell typeModuleShares the module with
FibroblastsHeparan Sulfate Remodeling
ECM remodeling
ALDH1A3, COL12A1, FAM171B, FHOD3, GREB1, HS6ST1, JMJD1C, MAP1LC3A +11 moreView in SCUBA

About the gene

SynonymsFA3, FAC, FACC
Chromosome9: 95099054-95426796
Predicted locationIntracellular
Essential geneNo
Protein classCancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Biological processDNA damage, DNA repair

Function

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.