SCUBA

FHOD3 — Formin homology 2 domain containing 3

FHOD3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FHOD3's module in each cell type

Cell typeModuleShares the module with
FibroblastsHeparan Sulfate Remodeling
ECM remodeling
ALDH1A3, COL12A1, FAM171B, FANCC, GREB1, HS6ST1, JMJD1C, MAP1LC3A +11 moreView in SCUBA

About the gene

SynonymsFHOS2, FLJ22297, FLJ22717, KIAA1695
Chromosome18: 36297713-36780220
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Predicted intracellular proteins
Molecular functionActin-binding

Function

Actin-organizing protein that may cause stress fiber formation together with cell elongation (By similarity). Isoform 4 may play a role in actin filament polymerization in cardiomyocytes

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.