FASTKD2 — FAST kinase domains 2
FASTKD2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FASTKD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | SWI-SNF DNA Repair chromatin regulation & transcription | CEBPZ, DDX18, EIF3A, EIF3B, G3BP1, HNRNPA0, HSPA9, ILF3 +21 more | View in SCUBA |
About the gene
| Synonyms | KIAA0971 |
|---|---|
| Chromosome | 2: 206765357-206796189 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | RNA-binding, rRNA-binding |
| Biological process | Ribosome biogenesis |
Function
Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt- rRNA), controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation. May play a role in mitochondrial apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.