CEBPZ — CCAAT enhancer binding protein zeta
CEBPZ belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CEBPZ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | NF-kB activation TCR/AP1/NFKb pathway | ABCF1, BCL2A1, BUD23, BZW2, CALR, DDX21, DENND4A, GNL3 +21 more | View in SCUBA |
| Gamma-delta T cells | Chromatin Epigenetic Regulation DNA/chromatin regulation | ADNP2, ARID4B, ELL2, ENSG00000285976, ETF1, HIPK1, JMJD1C, JMY +17 more | |
| Macrophages | RNA Splicing Regulation Housekeeping | ABCF1, CDC42SE1, CDC5L, CDV3, DNAJC7, DYNC1LI1, FGFR1OP2, GNL3 +13 more | View in SCUBA |
| Mucosal-associated invariant T cell | Autophagy & Trafficking Stress | ATG2A, B3GNT2, BEST1, CTPS1, ELOA, KANSL2, LITAF, MTFP1 +6 more |
About the gene
| Synonyms | CBF2, CTF2 |
|---|---|
| Chromosome | 2: 37201612-37231596 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
Stimulates transcription from the HSP70 promoter
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.