SCUBA

HNRNPA0 — Heterogeneous nuclear ribonucleoprotein A0

HNRNPA0 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

HNRNPA0's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsmRNA splicing factors
RNA processing
CALM1, CALM2, CKS2, CYCS, EIF4A3, HNRNPA2B1, HNRNPAB, MRPS6 +12 moreView in SCUBA
CD8⁺ T cellsmRNA Stability/Processing
RNA processing & translation
C19orf53, EDF1, GPX4, IMPDH2, NAP1L1, NHP2, PTMA, YBX1View in SCUBA
Gamma-delta T cellsmRNA Splicing Processing
RNA processing & translation
ARHGEF1, BECN1, CCNI, DENND4B, EID1, HNRNPDL, KLHDC4, LENG8 +18 more
Glial cellsProteostasis Stress Response
Stress
DNAJB6, EIF5, NUDT4, RSRC2, SQSTM1, TRIM8, UBE2D3, ZC3HAV1View in SCUBA
Goblet cellsChromatin RNA Regulation
chromatin regulation & transcription
ANP32A, CBX1, HDAC2, HNRNPM, KHDRBS1, NONO, RBMX, RCN2 +1 moreView in SCUBA
Innate lymphoid cellsmRNA Translation
RNA processing & translation
ABHD14B, ARHGDIA, CD2BP2, EEF2, EIF3L, GYPC, H2AJ, HNRNPDL +6 moreView in SCUBA
Lymphatic endothelialTranslation Elongation
RNA processing & translation
ANXA2, EEF1A1, EEF2, EIF1, FTH1, FTL, HNRNPA1, PTMA +2 moreView in SCUBA
MacrophagesProtein Biogenesis
Housekeeping
ATP6V0D1, B3GAT3, BUD23, C11orf58, CHD4, CNPY2, DAZAP1, DDX46 +23 moreView in SCUBA
Mucosal-associated invariant T cellER Stress UPR
Stress
DDIT3, DNAJB9, EIF4A1, GTF2B, HERPUD1, IDI1, LDHA, MAP1LC3B +9 more
Smooth muscle cellsmRNA Splicing Factors
RNA processing & translation
ATF4, BEX3, CLIC4, COX20, NAP1L1, NDUFA6, NME4, PCBP1 +7 moreView in SCUBA

About the gene

SynonymsHNRPA0
Chromosome5: 137745651-137754363
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionRibonucleoprotein, RNA-binding

Function

mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.