GABPB1 — GA binding protein transcription factor subunit beta 1
GABPB1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GABPB1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Mucosal-associated invariant T cell | T cell Quiescence T cell maturation | AGO2, AUTS2, BCL6, BRD1, CSNK1D, DHCR7, FOXO1, GAL3ST2 +13 more |
About the gene
| Synonyms | E4TF1-47, GABPB, GABPB2 |
|---|---|
| Chromosome | 15: 50275389-50355408 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a master regulator of nuclear-encoded mitochondrial genes (By similarity). (Microbial infection) Necessary for the expression of the Adenovirus E4 gene
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.