GCA — Grancalcin
GCA belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GCA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Hypoxia metabolic stress Stress | ARG2, ARL4D, AXIN2, BNIP3, CITED4, CNKSR2, GSTM3, ID3 +13 more | View in SCUBA |
| Macrophages | Fc Receptor Phagocytosis Lysosomal & pahgocytosis | ANXA6, C1orf162, CD37, FCGR1A, FCGR3A, FPR1, HNMT, HTRA1 +10 more | View in SCUBA |
| Monocytes | Classical Monocyte Trafficking Migration & adhesion | ANXA6, CKAP4, EMB, F5, MAP2K6, MPP7, MSRB1, PADI4 +4 more | View in SCUBA |
| Neutrophils | Neutrophil Differentiation Developmental | ABTB1, FRAT2, ICAM3, MANSC1, MNDA, MSL3, NFE2, QPCT +2 more |
About the gene
| Synonyms | GCL |
|---|---|
| Chromosome | 2: 162318840-162371595 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.