KIF21A — Kinesin family member 21A
KIF21A belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIF21A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Vesicular Trafficking Housekeeping | AP1S2, ARFIP2, BRD9, C2orf72, CAND1, EEA1, GM2A, HEXA +16 more | View in SCUBA |
About the gene
| Synonyms | FEOM1, FLJ20052 |
|---|---|
| Chromosome | 12: 39293228-39443390 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Motor protein |
Function
Processive microtubule plus-end directed motor protein involved in neuronal axon guidance. Is recruited by KANK1 to cortical microtubule stabilizing complexes (CMSCs) at focal adhesions (FAs) rims where it promotes microtubule capture and stability. Controls microtubule polymerization rate at axonal growth cones and suppresses microtubule growth without inducing microtubule disassembly once it reaches the cell cortex.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.