EEA1 — Early endosome antigen 1
EEA1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EEA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TRIM28-ZNF Repression DNA/chromatin regulation | B4GALT4, FSCN1, HSPA2, ISG20L2, MAP3K13, MLF1, MORN3, PABPC4 +7 more | View in SCUBA |
| Endothelial | Endothelial NO Activation Endothelial cell development | BCL6B, BLOC1S1, CD99, CDH13, COX5A, CREM, DDAH2, DDX46 +8 more | View in SCUBA |
| Glial cells | Reactive Glial Activation Activation | AEBP1, ATP5F1E, F2R, FN1, IFI16, POLR2L, PRSS23, PSMA4 | View in SCUBA |
| Lymphatic endothelial | Actomyosin Contractility Cytoskeletal | AFAP1L1, C1orf21, COBLL1, GNB1, MAP4, OSBPL8, PPP1R12A, ROCK1 +6 more | View in SCUBA |
| Macrophages | DNA Damage Repair Stress | ABCC5, ADAM28, AKAP9, AKNA, ATM, ATP10D, BAZ2A, CHD9 +27 more | View in SCUBA |
| Mucosal-associated invariant T cell | Immune Synapse Signaling TCR Signaling | APC, ARHGAP26, ASXL2, CD46, CPSF2, DOCK8, EIF4G3, EPB41 +21 more |
About the gene
| Synonyms | ZFYVE2 |
|---|---|
| Chromosome | 12: 92770637-92929331 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.