MAGI1 — Membrane associated guanylate kinase, WW and PDZ domain containing 1
MAGI1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MAGI1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Long-gene Nuclear Transcripts Technical artifact | ABCA10, ABCA5, ADCY9, EXOC6B, GABRA2, IL6R, INSR, MBNL1 +6 more | View in SCUBA |
About the gene
| Synonyms | AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3 |
|---|---|
| Chromosome | 3: 65353525-66038918 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted intracellular proteins |
Function
Plays a role in coupling actin fibers to cell junctions in endothelial cells, via its interaction with AMOTL2 and CDH5 (By similarity). May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.