EXOC7 — Exocyst complex component 7
EXOC7 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EXOC7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Vesicular Trafficking Housekeeping | ADD1, ANAPC5, COPG1, EFCAB14, GANAB, MAN2B2, MCM3AP, MED1 +10 more | |
| Macrophages | Golgi-Endosome Trafficking Vesicular traficking | ACSL4, ADPGK, ARRDC3, ATXN7L3B, CLN8, DDB1, DNAJC2, ETS2 +26 more | View in SCUBA |
About the gene
| Synonyms | BLOM4, EXO70, Exo70p, KIAA1067, YJL085W |
|---|---|
| Chromosome | 17: 76081016-76121576 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters |
| Biological process | Exocytosis, Protein transport, Transport |
Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity). It is required for neuron survival and plays an essential role in cortical development (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.