METTL15 — Methyltransferase like 15
METTL15 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
METTL15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | RNA Processing RNA processing & translation | C1orf56, CD53, CNOT6L, EVI2A, HNRNPH2, HSD17B11, MAPRE1, NOP53 +3 more | View in SCUBA |
About the gene
| Synonyms | FLJ33979, METT5D1 |
|---|---|
| Chromosome | 11: 28108248-28527041 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Methyltransferase, Transferase |
Function
N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.