MKKS — MKKS centrosomal shuttling protein
MKKS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MKKS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Antimicrobial Oxidative Defense Antibacterial | ADAMDEC1, ALDOA, APOL3, CALHM6, CLEC10A, COX16, CPVL, DEFA5 +30 more | View in SCUBA |
| Monocytes | Tissue-Resident Macrophage Lysosomal & pahgocytosis | AP2A2, BLVRB, CD163, FAH, FCGRT, HTRA1, MYO7A, RNASE1 +6 more | View in SCUBA |
About the gene
| Synonyms | BBS6 |
|---|---|
| Chromosome | 20: 10401009-10434222 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Chaperone |
| Biological process | Sensory transduction, Vision |
Function
Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.