ALDOA — Aldolase, fructose-bisphosphate A
ALDOA belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDOA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Interferon-Stimulated Genes Inflammation | CRTAP, DAZAP2, DDX39B, EIF4B, GDI1, GNB2, GRINA, GSTM2 +17 more | View in SCUBA |
| Macrophages | Antimicrobial Oxidative Defense Antibacterial | ADAMDEC1, APOL3, CALHM6, CLEC10A, COX16, CPVL, DEFA5, DEFA6 +30 more | View in SCUBA |
| Monocytes | Inflammatory Monocyte Activation Inflammatory | C11orf98, CLEC2B, CNIH4, CRIP1, GRINA, IFITM2, LEPROTL1, NBPF26 +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | ER Glycosylation & Ubiquitin Protein processing & ER | AIP, ATP5MG, COX6A1, COX6B1, ELOB, FIS1, GAPDH, KRTCAP2 +9 more | |
| Natural Killer cells | Septin Cytoskeletal Assembly Cytoskeleton & motility | EEF1G, MIF, NME2, PLAAT3, POLD4, SEPTIN1, SEPTIN2, SEPTIN6 | View in SCUBA |
About the gene
| Chromosome | 16: 30064164-30070457 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Lyase |
| Biological process | Glycolysis |
Function
Catalyzes the reversible conversion of beta-D-fructose 1,6- bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.