MOCS2 — Molybdenum cofactor synthesis 2
MOCS2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MOCS2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Proteostasis/Chaperonin Protein processing & ER | BST2, CARD16, CBR1, CCT3, CCT6A, DOK2, DYNLL1, HIKESHI +13 more |
About the gene
| Synonyms | MOCO1, MOCS2A, MOCS2B |
|---|---|
| Chromosome | 5: 53095679-53110063 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Molybdenum cofactor biosynthesis |
Function
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.