MPDU1 — Mannose-P-dolichol utilization defect 1
MPDU1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MPDU1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Glycan Precursor Biosynthesis Nutrient processing | ANXA7, APEH, ASL, ATP2A3, CC2D1A, CCDC124, CCND3, CLIC3 +30 more | View in SCUBA |
About the gene
| Synonyms | CDGIf, Lec35, PQLC5, SL15, SLC66A5 |
|---|---|
| Chromosome | 17: 7583529-7592789 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Transport |
Function
Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.