SCUBA

CCDC124 — Coiled-coil domain containing 124

CCDC124 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CCDC124's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsMitochondrial Translation
Mitochondrial & OxPhos
ARF5, CBX6, CISD3, DCTN2, DDA1, EIF4E2, FKBP3, GID8 +17 moreView in SCUBA
Gamma-delta T cellsTranscriptional Elongation Control
DNA/chromatin regulation
ANP32B, AP2M1, ARF5, AURKAIP1, CUEDC2, CYC1, DCTN3, ERH +19 more

About the gene

SynonymsLso2, oxs1
Chromosome19: 17933015-17943991
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processCell cycle, Cell division

Function

Ribosome-binding protein involved in ribosome hibernation: associates with translationally inactive ribosomes and stabilizes the nonrotated conformation of the 80S ribosome, thereby promoting ribosome preservation and storage. Also required for proper progression of late cytokinetic stages

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.