MPZ — Myelin protein zero
MPZ belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MPZ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Myelinating Schwann Cell Myelination | ALDH1A1, ARHGAP15, CXCL12, FCGR2B, MXRA8, NTM, PRNP, RNASE1 +1 more | View in SCUBA |
About the gene
| Synonyms | CMT1, CMT1B, CMT2I, CMT2J, HMSNIB, P0 |
|---|---|
| Chromosome | 1: 161304735-161309968 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
Function
Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.